B488D050-70x40x45-V2 Cyan Laser Module

Low-noise 488nm laser module optimized for flow cytometry, hematology analyzers, and DNA sequencing applications with exceptional stability

488nm
Cyan
488nm

Key Features

Noise Level < 0.1% RMS
Beam Quality M² < 1.3
Stability < 1% / 8hrs
Lifetime 10,000 hrs

Top Applications

🔬
Flow Cytometry
🩸
Hematology
🧬
DNA Sequencing
🔧
Semiconductor

Pricing Information

Quantity 1-10 $3,636
Quantity 11-50 $3,029
Quantity 51-100 $2,475
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Technical Specifications

Optical Specifications

Wavelength 488 ± 2 nm
Output Power 50 mW (max)
Power Stability < 1% RMS / 8 hrs
Noise (RMS) < 0.1% (10Hz-2MHz)
Beam Quality (M²) < 1.3
Beam Diameter 6.0 × 1.2 mm @ 300mm
Beam Divergence 0.3 mrad (H) / 0.5 mrad (V)
Polarization Linear, Vertical, > 20dB
Operating Mode CW

Electrical & Environmental

Operating Voltage 12 VDC
Operating Current < 2 A
Power Control APC (Auto Power Control)
Control Interface 8-pin Direct Plug
Operating Temp 15-35°C
Storage Temp -20 to 60°C
Humidity 10-90% RH
Dimensions 70 × 40 × 45 mm
Weight < 200 g

Performance Characteristics

Warm-up Time < 2 minutes to specified performance
MTTF (Mean Time To Failure) 5,000 - 10,000 hours @ 25°C
Beam Pointing Stability < 5 μrad/°C
Beam Height from Base 19 mm
Laser Class 3B

Applications

🔬

Flow Cytometry

Primary excitation source for FITC, GFP, and Alexa Fluor 488 channels. Ideal for cell sorting, immunophenotyping, and multi-parameter analysis with excellent signal-to-noise ratio.

🩸

Hematology Analyzers

Automated blood cell counting, white blood cell differential analysis, reticulocyte counting, and platelet analysis in clinical diagnostic instruments.

🧬

DNA Sequencing

Fluorescence detection in capillary electrophoresis, Sanger sequencing, fragment analysis, and real-time PCR applications.

🔧

Semiconductor Testing

Wafer inspection, defect detection, photolithography alignment, and quality control in semiconductor manufacturing processes.

📸

Confocal Microscopy

Live cell imaging, FRET analysis, calcium imaging with Fluo-4, and protein localization studies with minimal photobleaching.

🌊

Raman Spectroscopy

Excitation source for Raman scattering analysis, chemical identification, and material characterization in research and quality control.

Compatible Fluorophores

The 488nm wavelength is the industry standard for exciting green fluorophores:

  • FITC (Fluorescein)
  • GFP / EGFP
  • Alexa Fluor 488
  • CFSE
  • Cy2
  • SYBR Green
  • Oregon Green
  • Calcein / Fluo-4
  • BODIPY FL

Application Note

The 488nm wavelength represents the primary argon-ion laser line, making it the gold standard for fluorescence excitation. This wavelength provides optimal excitation efficiency for the most commonly used fluorophores while minimizing cellular autofluorescence, ensuring superior signal-to-background ratios in biological applications.

Features & Technology

Core Features

  • Ultra-low noise operation (< 0.1% RMS) for sensitive detection
  • Automatic Power Control (APC) maintains stable output
  • Direct diode technology for reliable operation
  • Grey anodized aluminum housing for thermal management
  • Linear vertical polarization with high extinction ratio (>20dB)
  • Compact form factor (70×40×45mm) for easy integration
  • Low power consumption (12V DC, <2A)
  • Fast warm-up time (<2 minutes)
  • Excellent beam pointing stability (<5 μrad/°C)
  • Long operational lifetime (5,000-10,000 hours)
  • Class 3B laser safety rating
  • RoHS and CE compliant design

Optical Characteristics

  • Gaussian beam profile (M² < 1.3)
  • Excellent wavelength stability
  • Low beam divergence
  • Consistent beam dimensions
  • Minimal astigmatism
  • High beam quality

Reliability Features

  • Wide operating temperature range
  • Humidity resistant design
  • Robust mechanical construction
  • Integrated thermal management
  • Over-current protection
  • Long-term power stability

Laser Technology

The B488D050-70x40x45-V2 utilizes advanced direct diode technology optimized for 488nm emission. This design ensures exceptional wavelength stability and low noise operation critical for fluorescence applications. The integrated Automatic Power Control (APC) system maintains consistent output power across the entire operating temperature range.

The 488nm wavelength is specifically chosen for its compatibility with common fluorophores and minimal overlap with cellular autofluorescence, making it ideal for life science applications requiring high sensitivity and specificity.

⚠️ Safety Information

Class 3B laser product. Avoid direct eye exposure. Use appropriate laser safety eyewear (OD 3+ @ 488nm). Follow all safety protocols per IEC 60825-1 and 21 CFR 1040.10. Ensure proper beam containment and interlocks.

Resources & Integration

💿 Software & Drivers

Available upon request.

🔧 Technical Resources

Available upon request.

System Integration

Mechanical Interface
  • 4 × φ 3.2 mounting holes
  • 19mm beam height from base
  • Compact 70×40×45mm footprint
  • Grey anodized aluminum housing
  • Front-exit beam aperture
Electrical Interface
  • 8-pin direct plug connector
  • 12V DC power input
  • Automatic Power Control (APC)
  • Master computer control option
  • Custom terminal configurations available
OEM Integration Support

Full OEM support available including custom configurations, extended warranties, volume pricing, and technical integration assistance. Contact our engineering team for specific requirements and customization options.

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